Day 106 (5p15.1-5p14.1): PRDM9, a gene shuffler

journal.pbio.1001211.g001 | Genome Year

Day 106 is a desert with only 4 protein-coding genes (browser view), including PRDM9 (PR domain zinc finger 9).

PRDM9 binds to DNA and is involved with meiosis, when your parents’ genes are shuffled in your sperm or eggs. PRDM9’s activity is responsible for recombination hotspots, places where meiotic shuffling happens much more than elsewhere. It may be especially important in evolution because variation could cause sterility both within and between species.

Click here to see all 8644679 letters of Day 106 with PRDM9 underlined.

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