Day 117 (5q22.2-5q23.1): the most common cause of colon cancer

Blausen_0246_ColorectalCancerhttps://en.wikipedia.org/wiki/Colorectal_cancer#/media/File:Blausen_0246_ColorectalCancer.png

Day 117 has 34 protein-coding genes (browser view) including APC (adenomatous polyposis coli).

APC is a tumor suppressor gene – its normal function is to control cell growth. APC is the most commonly mutated gene in colon cancer, and the most common mutation is c.4348C>T, which inserts a premature “stop” signal and destroys the protein.

Click here to see all 8644679 letters of Day 117 with the APC c.4348C>T mutation flashing.

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