Day 138 (6q21-6q22.31): an ancient centromere

778fig1https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675966/figure/F1/

Day 138 has 45 protein-coding genes (browser view). It includes a gene-poor region 6q22.1 which used to be a centromere 17 million years ago.

Centromeres can often move around in humans without any harmful changes. This 6q22.1 neocentromere was discovered by chance  by Cappozi et al. in a family when taking a karyotype, and through analysis of other primates was inferred to have been a centromere earlier in evolutionary history.

Click here to see all 8540299 letters of Day 138.

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