http://sonic.wikia.com/wiki/Sonic_the_Hedgehog_(Pre-Super_Genesis_Wave) Day 163 has 46 protein-coding genes (browser view) including SHH (sonic hedgehog).
This was a typical whimsical name for a gene discovered in flies, but the name has become controversial as mutations in the human gene cause severe developmental disorders.
Click here to see all 8386631 letters of Day 163 with SHH underlined.