Day 188 (8q11.21-8q12.1): kappa opioid receptor, target of salvia

800px-salvia_divinorum_-1https://en.wikipedia.org/wiki/Salvia_divinorum#/media/File:Salvia_divinorum_-1.jpg

Day 188 has 32 protein-coding genes (browser view), including OPKR1 (kappa-opioid receptor).

Like Day 143 (6q25.2-6q26): the mu opiod receptor, OPKR1 is an opioid receptor in the brain, but behaves differently. It may actually counteract the addictive mechanisms of the other opioid receptors. It is specifically targeted by the psychoactive plant salvia which is important to Aztec and Mazatec religious practice.

Click here to see all 8537567 letters of Day 188 with OPKR1 underlined.

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