Day 260 (12q23.3-12q24.22): an Asian alcohol-flush mutation


Day 260 has 78 protein-coding genes (browser view), including ALDH2 (aldehyde dehydrogenase 2 family (mitochondrial)).

Like the variant seen on Day 93 (4q22.3-4q24): an Asian innovation in alcohol dehydrogenase, a variant rs671/E504K  in ALDH2 is unique to Asia and influences alcohol metabolism. It leads to facial flushing and severe hangovers.

Click here to see all 8329707 letters of Day 260 with the ALDH2 E504K mutation flashing.

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