Day 266 (13q12.12-13q13.1): BRCA2

DNA cyclepath to Shelford To commemorate the National Cycle Network reaching 10,000 miles in September 2005, this mile of cyclepath was patterned with 10,257 stripes representing the human gene BRCA2, which codes for a DNA repair protein. Code: Adenine:Green, Cytosine:Blue, Guanine:Yellow, Thymine:Red. The path is part of Cycle Route 11 from London to Kings Lynn via Cambridge.https://en.wikipedia.org/wiki/BRCA2#/media/File:DNA_cyclepath_to_Shelford_-_geograph.org.uk_-_538440.jpg

DNA cyclepath to Shelford To commemorate the National Cycle Network reaching 10,000 miles in September 2005, this mile of cyclepath was patterned with 10,257 stripes representing the human gene BRCA2, which codes for a DNA repair protein. 

Day 266 has 49 protein-coding genes (browser view), including BRCA2, one of the two major breast and ovarian cancer susceptibility genes.

Like Day 6 (1p34.2-1p32.3): MUTYH, a DNA repairer and Day 55 (2q34-2q35): XRCC5, a DNA repairer discovered in hamsters, the normal role of BRCA2 is to repair DNA. It is expressed in breast tissue and mutations in BRCA1 and BRCA2 leave the tissue sensitive to carcinogenic mutations.

Click here to see all 8168881 letters of Day 266 with BRCA2 underlined.

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