Day 305 (16p12.1-16p11.2): BOLA2, a gene duplication specific to humans

nature19075-f1http://www.nature.com/nature/journal/v536/n7615/fig_tab/nature19075_F1.html

Day 305 has 142 protein-coding genes (browser view) including BOLA2 (bolA family member 2).

BOLA2 is a gene that is found duplicated in all humans but not in other primates, and it rapidly spread across the human population about 300,000 years ago Р a spread that is so rapid that it can only be explained through positive natural selection rather than drift. This same region is often associated with genetic differences in autism, which means it may have had an important role in brain evolution.

Click here to see all 8212576 letters of Day 305 with BOLA2 underlined.

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