Day 336 (20q11.21-20q12): the ITCH gene

http://simpsons.wikia.com/wiki/Itchy

Day 336 has 102 protein-coding genes (browser view) including ITCH (itchy E3 ubiquitin protein ligase).

ITCH is a ubiquitin ligase which marks proteins for destruction. It was discovered in mouse in 1998 and called itchy because of a fatal set of immune symptoms when the gene is mutated, including scarring from constant itching.

Click here to see all 8055520 letters of Day 336 with ITCH underlined.

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