Day 337 (20q12-20q13.13): TOP1, relieving the tension in DNA

http://gifsoup.com/view/5235626/topoisomerase-i-mechanism-of-action.html

Day 337 has 91 protein-coding genes (browser view) including TOP1 (topoisomerase 1).

Topoisomerase enzymes are critical to all life, so they are billions of years old. They relieve over-winding of DNA during replication. Attacking this enzyme in bacteria or cancer cells is an effective way to kill them.

Click here to see all 8055521 letters of Day 337 with TOP1 underlined.

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