Day 345 (19q13.2-19q13.33): the most important Alzheimer’s mutation

http://maturityanditsmuse.org/words-fail-us-dementia-and-the-arts-dementia-alzheimers-creativity-viaguardian/

Day 345 has 278 protein-coding genes (browser view) including APOE.

This gene is famous because¬†of two common variants in it that have a strong effect on Alzheimer’s risk. Two C alleles at the rs429358 SNP¬†increase the risk of late-onset Alzheimer’s by 12-fold.

Click here to see all 8373945 letters of Day 345 with the rs429358 SNP flashing.

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