Day 55 (2q34-2q35): XRCC5, a DNA repairer discovered in hamsters

Chinesedsaffahttps://en.wikipedia.org/wiki/Chinese_hamster#/media/File:Chinesedsaffa.jpg

 

Day 55 has 29 protein-coding genes (browser view), including XRCC5 (X-ray repair complementing defective repair in Chinese hamster cells 5). As the name implies, XRCC5 was discovered through experiments that used X-rays to damage cells from the Chinese hamster.

Radiation and carcinogens can cause DNA to suffer double-stranded breaks.  XRCC5 helps repair these through the non-homologous end joining process.

XRCC5 is so fundamental to life that it’s shared among all eukaryotes, meaning it’s at least 2 billion years old.

Click here to see the sequence of Day 55 with your XRCC5 gene underlined.

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