Day 63 (3p22.3-3p22.1): catenin beta, a moonlighting armadillo


Day 63 has 63 protein-coding genes, including CTNNB1 (catenin beta 1), also known as beta-catenin. Beta catenin helps cells stick to each other to form structured tissues, but also moonlights with a radically different role in the nucleus: regulating genes during development.

CTNNB1 is homologous to the armadillo gene in flies. CTNNB1 is shared with animals as distant as worms, meaning it is at least 500 million years old.

Click here to see the sequence of day 63 with your CTNNB1 gene underlined.


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