Day 73 (3q13.33-3q21.3): MCM2, a DNA-replicating protein


Day 73 has 81 protein-coding genes (browser view), including MCM2 (minichromosome maintenance complex component 2). The MCM2 protein is part of a ring of five proteins Рa heterohexamer Рthat wraps itself around DNA replication origins in preparation to replicate DNA before cells divide. This step of cell division is exquisitely controlled by the cell in order to prevent cancerous cell divisions.

The name “minichromosome maintenance” comes from the discovery of MCM proteins in yeast, in studies that used tiny artificial chromosomes to montior every step of the process.

Click here to see all 8621546 letters of Day 73, with MCM2 underlined.

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