Day 75 (3q22.3-3q24): three genes for scramblases

Day 75 has 48 protein-coding genes (browser view), including three of the five genes named phospholipid scramblases. Your cells are surrounded by a double layer of lipids, and there are usually different kinds of lipids on the inner and outer membrane. This asymmetry breaks down temporarily during cell injury and apoptosis, and this is thought to be due to scramblase enzymes that scramble the lipids between the two membranes. Interestingly, although these genes’ products are named scramblases, their activity as scramblases hasn’t been proven – other enzymes might be responsible.

Click here to see all 8621546 letters of Day 75, with PLSC1 (phospholipid scramblase 1) underlined.

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